The maxillofacial region may have the first manifestation of multiple myeloma

Abstract

Objective: this article aims to identify, through an integrative review, the primary manifestations of Multiple myeloma (MM) in the maxillofacial complex. Material and Methods: this integrative review was performed using the PubMed and Scopus databases, and included articles that reported the first manifestations of MM in
the maxillofacial region. The search was performed using the descriptors “oral manifestation” and “multiple myeloma”. Results: this integrative review describes 28 cases of MM reported in the literature where the first manifestations were in the maxillofacial region, emphasizing the importance of a complete oral clinical exam due to the highly variable clinical manifestations and radiographic or other imaging features, since multiple myeloma can be diagnosed at earlier stages. Conclusion: thus, it is essential that the healthcare professional has knowledge for the correct diagnosis and agility in this urgent treatment, in order to preserve the dental organ in the oral
cavity for a longer time.