A discussion on the effect of rhBMP-2 in the alveolar bone augmentation
Abstract
The aim of this paper is to review the literature about bone morphogenetic protein type 2 (BMP-2) and on the effect in the alveolar bone augmentation.
In 1965, the BMP was isolated by Marshal Urist, who showed that this protein extracted from bone narrow could induce bone neoformation when implanted in
sites without bone cells. Recently, a lot of studies have been looking for bone regeneration using BMPs without bone grafts. The present study it was concluded that the bone morphogenetic protein induces bone neoformation, being an alternative as a substitute to bone grafts and that new carrier discovery
is necessary to smooth stability of this carriers in receptor site.
In 1965, the BMP was isolated by Marshal Urist, who showed that this protein extracted from bone narrow could induce bone neoformation when implanted in
sites without bone cells. Recently, a lot of studies have been looking for bone regeneration using BMPs without bone grafts. The present study it was concluded that the bone morphogenetic protein induces bone neoformation, being an alternative as a substitute to bone grafts and that new carrier discovery
is necessary to smooth stability of this carriers in receptor site.
Keywords
Proteína morfogenética óssea; Fator de crescimento; Remodelação óssea.
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PDF (Português (Brasil))DOI: http://dx.doi.org/10.18363/rbo.v71n2.p.180
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